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Catalog |
BCC-002 |
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Product Name |
HATU;O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate |
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CAS |
148893-10-1 |
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EINECS |
604-662-7 |
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Molecular Formula |
C10H15F6N6OP |
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Molecular Weight |
380.23 |
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Appearance |
White or pale yellow crystalline powder |
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Assay |
≥99.0% |
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Water |
≤0.30% |
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Melting Point |
183-191℃ |
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Molecular structure |
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HATU is a premium-grade coupling reagent widely utilized in solid-phase peptide synthesis (SPPS) and organic chemistry for its exceptional efficiency in forming amide bonds. As a uronium-type activator, it minimizes racemization and ensures high-yield reactions, making it a staple in pharmaceutical manufacturing, bioconjugation, and advanced molecular research.
High Reactivity
Accelerates amide/peptide bond formation under mild conditions.
01
Low Epimerization
Ideal for synthesizing stereochemically sensitive compounds.
02
Pharmaceutical Grade
≥99% purity (HPLC), optimized for critical applications.
03
Broad Compatibility
Works effectively with Fmoc/t-Boc protection strategies.
04
- Peptide & oligonucleotide synthesis.
- Preparation of antibody-drug conjugates (ADCs) and PROTACs.
- Medicinal chemistry and high-throughput screening (HTS).
Packaging: Provide packaging in various specifications. Store at 4°C in a dry environment.
- Batch-specific certificates of analysis (COA) provided.
- Customizable packaging and technical support.
- Globally compliant with REACH, ISO 9001, and GMP guidelines.
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